@NickOttens I have just stumbled upon the research of Prof. Anahid Jewett from UCLA on NK Cells. The potency of these cells could be an adjuvant biomarker for aging. You may want to look into that research and its synergy with probiotics and/or Terpenes.
Perhaps another option of a surrogate marker for aging are the load of senescent cells. As we age, our immune system becomes less efficient in removing those cells. A recent journal club [url="a16z Journal Club: Slaying the Sleeper Cells of Aging with CAR T - Andreessen Horowitz Inbox x Yoav Medan <yoav@medan-il.com> 06:37 (4 hours ago) to me https://a16z.com/2020/08/09/slaying-sleeper-cells-aging-car-t/"]A16Z podcast[/url] (Andreseen-Horowitz) talks about CAR-T approach to age reversal by remove excess senescence. In paranthesis, I wonder if the gut microbiome does not have a "say" in this process. Time will tell
The “killer app” of nanotechnology is “nanobots,” which are blood-cell sized robots that can travel in the blood stream destroying pathogens, removing debris, correcting DNA errors, and reversing aging processes.
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379907/
As consider focusing on rejuvenating the immune system, we've started a separate discussion about biomarkers that would be relevant to such a prize.